This juicy, tender, and flavor-packed homemade meatloaf is topped with a sweet and tangy glaze that caramelizes to perfection — a comforting classic you'll actually look forward to. Ideal for family dinners and guaranteed to be a new favorite.
Preheat oven to 350°F (175°C). Line a rimmed baking sheet with parchment paper.
Sauté the chopped onion in olive oil over medium heat until golden and soft. Set aside to cool slightly.
In a large bowl, combine ground beef, cooled onions, garlic, eggs, milk, breadcrumbs, parsley, ketchup, salt, pepper, and Italian seasoning. Mix gently with your hands until just combined.
Form the meat mixture into a loaf (about 8x4 inches) on the prepared baking sheet. Bake uncovered for 40 minutes.
While it bakes, mix ketchup, vinegar, brown sugar, garlic powder, and onion powder in a bowl to create the glaze.
After 40 minutes, remove the meatloaf and brush the glaze evenly on top. Return to oven and bake for an additional 20 minutes, or until the internal temperature reaches 160°F (71°C).
Let the meatloaf rest for 10–15 minutes before slicing to allow juices to redistribute. Serve warm.
Notes
Mix meat gently to keep it tender.
Shape it free-form for better texture.
Always rest the meatloaf before slicing for best results.